Axsome Therapeutics, Inc. (AXSM) - Stock Analysis

Last updated: Jul 25, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Strong near-term catalyst stack: FDA approved AUVELITY for agitation associated with dementia due to Alzheimer's disease on 2026-04-30/05-01, Q1 2026 product revenue rose 57% YoY to $191.2M, NDA submitted for AXS-12, SUNOSI patent settlement extended protection, and the stock is up about 33% over 21 trading days.

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Idea window: 5/5/2026 – 5/12/2026Sector: Healthcare

AI Analyst Overview

Last Price
$234.20
Market Cap
$11.14B
1D Return
-1.75%
YTD Return
+28.23%

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Valuation Metrics

P/E
-58.9
P/B
203.0
P/S
15.7
EV/EBITDA
-65.8
Div Yield

Price Behavior

5.0

Key Price Behavior Insights: • Oversold rebound • Range-bound action • Resistance failure Support Level: $236-$237 Resistance Level: $249-$250 Over the last month, AXSM has been range-bound and volatile, rebounding from an oversold drop to $221.64 but still needing a reclaim of $249-$250 to confirm upside.

rebound
AXSM

Sentiment & News

7.0

Key News Insights: • Pediatric ADHD • NDA accepted • Earnings ahead Axsome's near-term outlook improved on pediatric ADHD trial starts and FDA acceptance of AXS-12 for narcolepsy cataplexy, with upcoming earnings and late-stage catalysts keeping the stock event-driven.

ClinicalCatalyst
PipelineMomentum
AI

AI Summary

7.0
Positive

AXSM is evolving from a single-product biotech into a credible commercial CNS platform with 57% Q1 revenue growth and an expanded AUVELITY addressable market, but the stock now hinges on whether management can keep executing fast enough to justify a valuation that already reflects much of this progress.

Growth
Valuation
Execution
AI summary updated 2 days ago

Description

Axsome Therapeutics is a U.S.-based biopharmaceutical company developing treatments for central nervous system disorders. Its late-stage pipeline includes a depression candidate (AXS-05) with additional trials in Alzheimer's-related agitation and prior smoking cessation data, a migraine treatment that completed Phase III testing (AXS-07), and Phase III programs for narcolepsy (AXS-12) and fibromyalgia (AXS-14). The company has a research collaboration with Duke University and was founded in 2012 in New York City.

Idea History

DateCloseTickerCompanySummaryStatusP/L
May 5May 12AXSMAxsome Therapeutics, Inc.
Strong near-term catalyst stack: FDA approved AUVELITY for agitation associated with dementia due to Alzheimer's disease on 2026-04-30/05-01, Q1 2026 product revenue rose 57% YoY to $191.2M, NDA submitted for AXS-12, SUNOSI patent settlement extended protection, and the stock is up about 33% over 21 trading days.
Closed+0.4%
Jan 1Jan 8AXSMAxsome Therapeutics, Inc.
Axsome Therapeutics is a hot idea with key upcoming FDA priority review of AXS-05 and NDA filing for AXS-12, strong Q3 revenue growth, and robust technical momentum. Despite operating losses and governance risks, its near-term regulatory catalysts provide potential for significant short-term price appreciation.
Closed-8.3%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.