Insmed Incorporated (INSM) - Stock Analysis

Last updated: Jan 13, 2026

HealthcareClosed

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Insmed (INSM) is supported by FDA approvals, strong Q3 revenue growth (+22% ARIKAYCEÂŽ), bullish technical momentum (+24.5% over 21 days), and raised guidance reflecting commercial traction. Despite continuing losses and high valuation, ongoing pipeline catalysts and significant liquidity underpin a moderate short-term upside case.

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Idea window: 11/24/2025 – 12/1/2025Sector: Healthcare

AI Analyst Overview

Last Price
$161.42
Market Cap
$34426.60
1D Return
+1.35%
YTD Return
-7.25%

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Valuation Metrics

P/E
-28.9
P/B
36.1
P/S
77.0
EV/EBITDA
-32.4
Div Yield
—

Fundamental Analysis

5.0

Key Financial Insights: • High gross margins • Negative free cashflow • Large operating losses INSM shows improved operating trends and strong gross margins with adequate short-term liquidity but remains a cash-burning, loss-making company with heavy expenses and an extremely rich market valuation.

CashBurn
HighGross

Price Behavior

6.0

Key Price Behavior Insights: • Lower highs • Lower lows • Support tested Support Level: $160–$165 Resistance Level: $170 Over the last month INSM reversed from a mid‑December peak (~$198.46) into a clear short‑term downtrend to $167.72, holding above longer‑term support around $160–$165 but needing a break above $170 to signal a recovery.

bearish
watchlist

Sentiment & News

6.0

Key News Insights: • Clinical setback • Strong Brinsupri • Insider selling Insmed experienced sharp volatility from late‑2025 clinical setbacks and legal scrutiny coupled with insider selling, tempered by strong Brinsupri sales, new pipeline moves, regulatory approvals, and upbeat 2026 guidance.

pipeline
legal
AI

AI Summary

6.0
Neutral

Insmed's shift from development to commercial hinges on BRINSUPRI/ARIKAYCE converting early launch volumes into durable, payer‑backed revenue and rapid margin improvement—failure to accelerate the revenue ramp or curb SG&A/R&D growth will likely force dilutive financing and could wipe out the premium valuation.

CommercialPivot
DilutionRisk
ExecutionCritical
AI summary updated 6 days ago

Description

Insmed is a biopharmaceutical company that develops and commercializes therapies for patients with serious and rare diseases, and it markets ARIKAYCE for adult Mycobacterium avium complex lung disease as part of a combination antibacterial regimen. The company’s pipeline includes Brensocatib, an oral reversible dipeptidyl peptidase 1 inhibitor in development for bronchiectasis and other neutrophil-mediated conditions, and an inhaled treprostinil palmitil prodrug being studied for pulmonary arterial hypertension and other rare pulmonary disorders.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Nov 24Dec 1INSMInsmed Incorporated
Insmed (INSM) is supported by FDA approvals, strong Q3 revenue growth (+22% ARIKAYCEÂŽ), bullish technical momentum (+24.5% over 21 days), and raised guidance reflecting commercial traction. Despite continuing losses and high valuation, ongoing pipeline catalysts and significant liquidity underpin a moderate short-term upside case.
Closed+2.2%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.