Insmed Incorporated (INSM) - Stock Analysis

Last updated: Sep 5, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Insmed has strong biotech catalysts: Q2 revenue was $425.5M, BRINSUPRI revenue grew 49% sequentially to $309.2M, 2026 BRINSUPRI guidance was raised to $1.25B-$1.40B, TPIP data were favorable, and the Q2 loss of $0.52 beat the $0.69 consensus loss.

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Idea window: 8/7/2026 – 8/14/2026Sector: Healthcare

AI Analyst Overview

Last Price
$129.41
Market Cap
$28.05B
1D Return
+1.67%
YTD Return
-25.64%

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Valuation Metrics

P/E
-31.5
P/B
37.1
P/S
24.7
EV/EBITDA
-37.1
Div Yield
—

Fundamental Analysis

6.0

Key Financial Insights: • Strong liquidity • Negative cash flow • High valuation INSM's improving revenue, margins, EBITDA, and liquidity are offset by persistent cash burn, leverage, accumulated losses, and an expensive valuation.

Liquidity
CashBurn

Price Behavior

5.0

Key Price Behavior Insights: • Support defended • Resistance stalled • Breakout needed Support Level: $121.39–$121.82; deeper support at $118.54 Resistance Level: $126.63–$126.68 INSM rebounded from $118.54 support but remains below $126.63–$126.68 resistance over the last month, so wait for a breakout before turning bullish.

INSM
Watchlist

Sentiment & News

8.0

Key News Insights: • Raised BRINSUPRI Guidance • Japan Market Approval • Narrower Quarterly Loss Insmed's strong BRINSUPRI-led growth, raised guidance, narrowed losses, and Japan approval reinforce a positive commercial outlook despite ongoing unprofitability.

Insmed
BiotechGrowth
AI

AI Summary

7.0
Positive

INSM is transitioning into a commercial respiratory platform as BRINSUPRI's rapid growth builds a potential self-funding base, but at ~25x sales investors should wait for sustained adoption and positive free-cash-flow conversion before underwriting further upside.

CommercialScale
ValuationRisk
CashFlow
AI summary updated 6 days ago

Description

Insmed is a biopharmaceutical company that develops and commercializes therapies for patients with serious and rare diseases, and it markets ARIKAYCE for adult Mycobacterium avium complex lung disease as part of a combination antibacterial regimen. The company’s pipeline includes Brensocatib, an oral reversible dipeptidyl peptidase 1 inhibitor in development for bronchiectasis and other neutrophil-mediated conditions, and an inhaled treprostinil palmitil prodrug being studied for pulmonary arterial hypertension and other rare pulmonary disorders.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Aug 7Aug 14INSMInsmed Incorporated
Insmed has strong biotech catalysts: Q2 revenue was $425.5M, BRINSUPRI revenue grew 49% sequentially to $309.2M, 2026 BRINSUPRI guidance was raised to $1.25B-$1.40B, TPIP data were favorable, and the Q2 loss of $0.52 beat the $0.69 consensus loss.
Closed-5.6%
Jul 8Jul 15INSMInsmed Incorporated
Strong healthcare momentum with concrete clinical and commercial support: shares rose 22.7% over 21 trading days, Q1 2026 revenue was $306.0M, ENCORE met its primary and key secondary endpoints, and pipeline activity includes TPIP Phase 3 initiation.
Closed-5.8%
Apr 1Apr 8INSMInsmed Incorporated
Fresh positive Phase 3 ENCORE topline (3/23) and strong 2026 revenue guidance (BRINSUPRI ≥$1B, ARIKAYCE $450–470M) have driven ~9.8% 21-day ROC and price ~13% above the 21-day SMA. With Phase 2b CEDAR topline due in Q2 2026, the stock is a high-risk but well-defined event-driven long for the coming days.
Closed-2.8%
Nov 24Dec 1INSMInsmed Incorporated
Insmed (INSM) is supported by FDA approvals, strong Q3 revenue growth (+22% ARIKAYCEÂŽ), bullish technical momentum (+24.5% over 21 days), and raised guidance reflecting commercial traction. Despite continuing losses and high valuation, ongoing pipeline catalysts and significant liquidity underpin a moderate short-term upside case.
Closed+2.2%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.