Krystal Biotech, Inc. (KRYS) - Stock Analysis

Last updated: Sep 6, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Rose 14.6% over 21 sessions and closed at the assessment-period high. Q2 VYJUVEK revenue reached $119.2 million, while 94.6% gross margin, strong profitability, international launches, and second-half 2026 clinical readouts support continuation.

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Idea window: 9/3/2026 – 9/10/2026Sector: Healthcare

AI Analyst Overview

Last Price
$347.00
Market Cap
$10.23B
1D Return
+0.42%
YTD Return
+40.75%

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Valuation Metrics

P/E
42.0
P/B
7.5
P/S
23.2
EV/EBITDA
46.8
Div Yield

Fundamental Analysis

8.0

Key Financial Insights: • High Profitability • Strong Liquidity • Low Leverage KRYS has exceptional profitability, liquidity, and minimal debt, but its premium valuation and slowing quarterly momentum warrant caution.

StrongFundamentals
ValuationRisk

Price Behavior

6.0

Key Price Behavior Insights: • Positive monthly trend • Key support test • Breakout resistance Support Level: $351–$352 Resistance Level: $371–$372 KRYS remains constructively bullish over the last month but needs to hold $351–$352 and clear $371–$372 to resume upside after a sharp selloff.

Bullish
Volatile

Sentiment & News

6.0

Key News Insights: • Shares Rally • Vyjuvek Growth • Conference Catalyst KRYS gained on Vyjuvek growth and pipeline optimism, with investor attention shifting to its upcoming healthcare conference.

KRYS
BiotechGrowth
AI

AI Summary

7.0
Positive

KRYS is now a profitable, cash-rich rare-disease commercial company, but at ~21x sales its premium valuation leaves little room for VYJUVEK growth to slow or pipeline readouts to disappoint; investors should favor holding/adding only if VYJUVEK penetration and European launches sustain growth while treating 2026 pipeline assets as upside optionality, not embedded value.

CommercialStrength
ValuationRisk
PipelineCatalyst
AI summary updated 5 days ago

Description

Krystal Biotech is a clinical-stage biotechnology company developing redosable gene therapies for serious, primarily rare, dermatologic and genetic conditions. Its lead candidate, beremagene geperpavec (B-VEC), is in Phase III for dystrophic epidermolysis bullosa, while a portfolio of other programs spans early- and preclinical development for congenital ichthyosis, netherton syndrome, cystic fibrosis and multiple dermatology indications including aesthetic applications. The company was founded in 2015 and is headquartered in Pittsburgh, Pennsylvania.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Sep 3Sep 10KRYSKrystal Biotech, Inc.
Rose 14.6% over 21 sessions and closed at the assessment-period high. Q2 VYJUVEK revenue reached $119.2 million, while 94.6% gross margin, strong profitability, international launches, and second-half 2026 clinical readouts support continuation.
Closed-7.0%
Nov 3Nov 10KRYSKrystal Biotech, Inc.
Selected as a speculative near-term buy ahead of Nov 3 earnings supported by FDA label expansion, upcoming European/Japanese launches, strong margins, and positive biotech sector trends, with cautious risk management due to seasonal sales softness and inventory build.
Closed+0.9%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.