Replimune Group, Inc. (REPL) - Stock Analysis

Last updated: Jul 25, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Speculative but strong event-driven momentum after FDA agreed on a resubmission path for RP1 plus nivolumab melanoma BLA, with supportive ASCO clinical updates and roughly 132% gain over 20 trading days.

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Idea window: 6/22/2026 – 6/29/2026Sector: Healthcare

AI Analyst Overview

Last Price
$6.20
Market Cap
$717.56M
1D Return
-28.22%
YTD Return
-36.27%

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Valuation Metrics

P/E
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P/B
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P/S
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EV/EBITDA
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Div Yield
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Price Behavior

4.0

Key Price Behavior Insights: • Failed Rebounds • Key Support Test • Overhead Resistance Support Level: $9.50 Resistance Level: $11.00-$11.60 REPL is in a fragile short-term downtrend after failing repeatedly at $11.0-$11.6, with near-term support around $9.5 that must hold to prevent further weakness.

REPL
downtrend

Sentiment & News

6.0

Key News Insights: • FDA acceptance • August decision • Legal scrutiny Replimune's RP1 melanoma filing was accepted by the FDA, keeping a potential August decision on track, though an advisory review and shareholder investigation add near-term uncertainty.

REPL
governance
AI

AI Summary

5.0
Neutral

Replimune is now a near-term FDA binary trade rather than a long-duration platform story: approval of the resubmitted RP1 BLA could sharply re-rate the stock, but any FDA pushback would likely hit a cash-burning, single-asset biotech with limited downside resilience.

FDA
BinaryEvent
RegulatoryRisk
AI summary updated 3 days ago

Description

Replimune Group, Inc. is a biotechnology company developing oncolytic immuno-gene therapies for cancer using its proprietary Immunotherapy platform. Its lead candidate, RP1, is a selectively replicating herpes simplex virus 1 therapy being evaluated in clinical trials for solid tumors and cutaneous squamous cell carcinoma, alongside earlier-stage programs including RP2 and RP3. The company was founded in 2015 and is based in Woburn, Massachusetts.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Jun 22Jun 29REPLReplimune Group, Inc.
Speculative but strong event-driven momentum after FDA agreed on a resubmission path for RP1 plus nivolumab melanoma BLA, with supportive ASCO clinical updates and roughly 132% gain over 20 trading days.
Closed+0.2%
Jun 10Jun 17REPLReplimune Group, Inc.
Speculative biotech momentum candidate: stock rose about 113% over 21 trading days, helped by 2026-05-29 FDA alignment on a path forward for RP1 plus nivolumab BLA resubmission/reconsideration and ASCO clinical updates on 2026-05-30 and 2026-05-31.
Closed+18.1%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.