Replimune Group, Inc. (REPL) - Stock Analysis

Last updated: Sep 6, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Speculative but strong event-driven momentum after FDA agreed on a resubmission path for RP1 plus nivolumab melanoma BLA, with supportive ASCO clinical updates and roughly 132% gain over 20 trading days.

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Idea window: 6/22/2026 – 6/29/2026Sector: Healthcare

AI Analyst Overview

Last Price
$13.24
Market Cap
$1.11B
1D Return
-8.37%
YTD Return
+36.21%

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Valuation Metrics

P/E
-4.2
P/B
12.1
P/S
0.0
EV/EBITDA
—
Div Yield
—

Fundamental Analysis

3.0

Key Financial Insights: • Strong Liquidity • Heavy Cash Burn • Rising Dilution REPL's strong liquidity is outweighed by severe losses, negative free cash flow, rising leverage, and dilution risk, making it a high-risk funding-dependent investment.

Liquidity
CashBurn

Price Behavior

6.0

Key Price Behavior Insights: • Upward monthly trend • Recent pullback • Key range breakout Support Level: $14.70–$14.80 Resistance Level: $15.80–$16.00 REPL remains bullish over the last month but is consolidating after a $15.98 peak; hold $14.70–$14.80 support and break $15.80–$16.00 resistance for renewed upside.

Momentum
Volatility

Sentiment & News

2.0

Key News Insights: • FDA Disclosure Claims • Lead Plaintiff Deadline • Litigation Overhang Replimune faces repeated shareholder-litigation notices alleging inadequate FDA-risk disclosures around RP1, creating continued legal and sentiment pressure.

LegalRisk
InvestorAlert
AI

AI Summary

4.0
Negative

REPL's FDA-approved TUDRIQEV shifts the thesis from speculative platform biotech to a launch-and-financing execution story, but with heavy cash burn, no reported revenue, and likely dilution, investors should wait for early prescription/reimbursement traction before underwriting expansion upside.

CommercialLaunch
DilutionRisk
FDAApproval
AI summary updated 4 days ago

Description

Replimune Group, Inc. is a biotechnology company developing oncolytic immuno-gene therapies for cancer using its proprietary Immunotherapy platform. Its lead candidate, RP1, is a selectively replicating herpes simplex virus 1 therapy being evaluated in clinical trials for solid tumors and cutaneous squamous cell carcinoma, alongside earlier-stage programs including RP2 and RP3. The company was founded in 2015 and is based in Woburn, Massachusetts.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Jun 22Jun 29REPLReplimune Group, Inc.
Speculative but strong event-driven momentum after FDA agreed on a resubmission path for RP1 plus nivolumab melanoma BLA, with supportive ASCO clinical updates and roughly 132% gain over 20 trading days.
Closed+0.2%
Jun 10Jun 17REPLReplimune Group, Inc.
Speculative biotech momentum candidate: stock rose about 113% over 21 trading days, helped by 2026-05-29 FDA alignment on a path forward for RP1 plus nivolumab BLA resubmission/reconsideration and ASCO clinical updates on 2026-05-30 and 2026-05-31.
Closed+18.1%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.