Theravance Biopharma, Inc. (TBPH) - Stock Analysis

Last updated: Jan 14, 2026

HealthcareClosed

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Theravance Biopharma benefits from record sales growth, upcoming Phase 3 CYPRESS data expected Q1 2026 as a key catalyst, positive technical momentum (+27% last month), and strong sector tailwinds, supporting near-term upside despite ongoing losses and high valuation.

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Idea window: 12/5/2025 – 12/12/2025Sector: Healthcare

AI Analyst Overview

Last Price
$20.01
Market Cap
$1013.96
1D Return
-0.50%
YTD Return
+6.95%

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Valuation Metrics

P/E
34.5
P/B
4.3
P/S
12.6
EV/EBITDA
-39.2
Div Yield
—

Fundamental Analysis

7.0

Key Financial Insights: • High cash balance • Negative operating history • Elevated valuation TBPH's liquidity and leverage improved materially by 2025-09-30, but sustained operating losses, negative free cash flow and large retained deficits undermine that strength and the stock appears richly valued.

Liquidity
StructuralRisk

Price Behavior

7.0

Key Price Behavior Insights: • Steady upward trend • Near-term support • Profit-taking risk Support Level: $18.00–$18.50 Resistance Level: $19.00 (recent high $20.33) Over the last month TBPH has shown a steady climb from about $18.16 to $20.33, holding $18.00–$18.50 as near-term support after clearing $19.00 and approaching $20.30 where profit-taking could appear.

Bullish
Watchlist

Sentiment & News

7.0

Key News Insights: • Analyst 42% upside • Assenagon stake surge • Momentum ratings rise Investor and analyst momentum for Theravance Biopharma (TBPH) strengthened into late 2025–early 2026, driven by bullish Zacks/momentum calls, a ~42% analyst upside projection, and a >1,600% institutional stake increase.

Bullish
Institutional
AI

AI Summary

6.0
Neutral

TBPH has shifted into a hybrid commercial‑and‑clinical story where growing YUPELRI revenue and ~$75M of near‑term partner milestones materially de‑risk the runway and justify a floor, but the stock remains binary—size positions for a single Phase‑3 ampreloxetine readout that can sharply re‑rate or reverse the thesis if negative or delayed.

CommercialStrength
BinaryRisk
CYPRESS
AI summary updated 4 days ago

Description

Theravance Biopharma is a biopharmaceutical company that researches, develops and commercializes respiratory medicines across the United States, Europe and Asia, with YUPELRI sold as a nebulized, once-daily therapy for COPD. Its clinical pipeline includes inhaled and gut-targeted small molecules—notably several JAK inhibitors and other candidates addressing pulmonary and gastrointestinal disorders—alongside later-stage programs for autonomic and motility conditions. The company maintains licensing and collaboration agreements with major pharmaceutical partners and is incorporated in 2013 with headquarters in George Town, Cayman Islands.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Dec 5Dec 12TBPHTheravance Biopharma, Inc.
Theravance Biopharma benefits from record sales growth, upcoming Phase 3 CYPRESS data expected Q1 2026 as a key catalyst, positive technical momentum (+27% last month), and strong sector tailwinds, supporting near-term upside despite ongoing losses and high valuation.
Closed-2.1%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.