Tempus AI, Inc. (TEM) - Stock Analysis

Last updated: Sep 20, 2026

Research Idea

Research content for general circulation. Not individualized advice. Methodology & Disclosures

Rose about 30% over 21 sessions and 36% from September 10 to September 17. Positive cancer-vaccine validation, the planned Personalis acquisition, new product and FDA milestones, and first-time positive adjusted EBITDA support the move.

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Idea window: 9/17/2026 – 9/24/2026Sector: Healthcare

AI Analyst Overview

Last Price
$66.12
Market Cap
$11.98B
1D Return
-2.20%
YTD Return
+11.97%

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Valuation Metrics

P/E
-47.3
P/B
27.3
P/S
8.4
EV/EBITDA
-146.8
Div Yield
—

Fundamental Analysis

5.0

Key Financial Insights: • Profitability Rebound • Negative Cash Flow • Rising Leverage TEM's profitability improved sharply in the latest quarter, but persistent cash burn, rising leverage, and a demanding valuation warrant caution despite strong liquidity.

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LeverageRisk

Price Behavior

6.0

Key Price Behavior Insights: • Strong breakout • Resistance rejection • Key support Support Level: $68.00–$70.00 Resistance Level: $80.00–$81.00 TEM gained 17% over the last month but faces pullback risk near $80–81 resistance, with $68–70 key support to hold.

Momentum
PullbackRisk

Sentiment & News

6.0

Key News Insights: • Analyst upgrades • ARPA-H funding • Valuation caution Tempus AI's surge reflects analyst optimism, AI-healthcare catalysts and Merck-related momentum, though its rapid run-up raises near-term valuation risk.

TempusAI
HealthcareAI
AI

AI Summary

6.0
Neutral

TEM's investment case has shifted to a reimbursement-driven operating-leverage story, but at ~$80 investors should wait for proof that xT/xF reimbursement converts into sustained positive operating cash flow, as a shortfall in payer adoption or Personalis integration could sharply pressure its premium valuation.

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CashFlowValidation
AI summary updated 36 days ago

Description

Tempus AI, Inc. is a healthcare technology company that performs molecular diagnostics, including next-generation sequencing, PCR profiling, genotyping and anatomic pathology for healthcare providers, pharmaceutical and biotechnology firms, and researchers. It also licenses a de-identified, linked clinical–molecular–imaging dataset and offers analytics, cloud compute tools, clinical trial matching, algorithmic oncology tests and software for test ordering and research workflows. The company entered strategic collaborations with AstraZeneca and Pathos AI, was incorporated in 2015, changed its name from Tempus Labs in January 2023, and is headquartered in Chicago, Illinois.

Idea History

DateCloseTickerCompanySummaryStatusP/L
Sep 17Sep 24TEMTempus AI, Inc.
Rose about 30% over 21 sessions and 36% from September 10 to September 17. Positive cancer-vaccine validation, the planned Personalis acquisition, new product and FDA milestones, and first-time positive adjusted EBITDA support the move.
Closed+2.3%
Dec 9Dec 16TEMTempus AI, Inc.
Tempus AI exhibits strong near-term growth supported by exceptional Q3 2025 results (85% revenue growth, first positive adjusted EBITDA) and strategic FDA clearances and collaborations. Despite recent price volatility and unresolved litigation risks, accelerating genomics testing and data licensing growth underline concrete short-term return potential.
Closed-10.2%
Research content for educational purposes only. Not investment advice. All decisions are your responsibility.